Research Areas

BIOINFORMATICS AND FUNCTIONAL GENOMICS

Bioinformatics and Genomics unit (B&Gu)

Raffaele Adolfo Calogero

 

Computational Biology Unit

Paolo Provero

 

The Functional Genomics Core Facility

Roberto Piva

 

CARDIOVASCULAR RESEARCH

Angiogenesis/Vasculogenesis in solid tumors

Benedetta Bussolati - Giovanni Camussi

 

Role of the phosphoinositol kinases for heart hypertrophy and in tumor formation

Emilio Hirsch

 

Metabolic and cellular signaling during cardiovascular homeostasis
Massimo Santoro

 

Role of the axis IL-6/STAT3/complement in regulating chronic inflammation and heart auto-immunity

Valeria Poli

 

Mechanisms of heme toxicity on the cardiovascular system

Emanuela Tolosano

 

CANCER BIOLOGY

Signalling platforms in normal and transformed cells: molecular and functional characterisation and translational strategies

Defilippi Paola - Turco Emilia

 

Signalling pathways involved in cancer transformation, progression and resistance to therapy

Sara Cabodi

 

Morgana, a CHORD-containing protein, in tumor onset and progression

Mara Brancaccio

 

Role of the phosphoinositol kinases for heart hypertrophy and in tumor formation

Emilio Hirsch

 

A Roadmap To Personalized Treatment Of Non Hodgkin Lymphomas (NHL)

Roberto Piva

 

Correlations between energy metabolism, calcium homeostasis, tumor stroma and tumor growth 

Valeria Poli

 

MicroRNAs and adhesion molecules involved in tumor progression

Daniela Taverna

 

Impact of heme/iron metabolism on tumor cell growth and sensitivity to therapy

Emanuela Tolosano

 

TUMOR IMMUNOLOGY

The road towards vaccine that prevent tumor formation
Federica Cavallo

 

INFLAMMATION

Role of the phosphoinositol kinases for heart hypertrophy and in tumor formation

Emilio Hirsch

 

Role of the axis IL-6/ STAT3 in regulating chronic inflammation and tumor onset 

Valeria Poli

 

IRON METABOLISM

Identification and functional characterization of genes involved in heme-iron metabolism

Emanuela Tolosano

 

MOLECULAR IMAGING

Design and testing of targeting and responsive probes for Molecular Imaging

Silvio Aime

 

DEVELOPMENTAL BIOLOGY

Metabolic and cellular signaling during cardiovascular homeostasis

Massimo Santoro

 

Genetics of Development

Giorgio Roberto Merlo

 

NEUROSCIENCE

Molecular and cellular neuroscience

Ferdinando Di Cunto 

 

Genetics of Development

Giorgio Roberto Merlo

 

Investigation of the molecular mechanisms linking heme metabolism to the degeneration of sensory neurons

Emanuela Tolosano

 

STEM CELL RESEARCH

Molecular mechanisms driving stem cell differentiation and the potential therapeutic applications of stem cells

Enzo Calautti

 

Stem cells and regenerative medicine
Fiorella Altruda

 

Regenerative Medicine

Benedetta Bussolati - Giovanni Camussi

 

Genetics of Development

Giorgio Roberto Merlo